Agilent 1290 Infinity II Bio HPLC System with Advanced Detection Suite

System includes:

• Solvent tray
• G7131A Bio Flexible Pump
• G7137A Bio Multisapler
• G7116B Multicolumn Thermostat (MCT)
• G7117B Diode Array Detector (DAD)
• G7121B Fluorescence Detector (FLD) Spectra
• Wyatt Optilab dRI Detector (2022 model)
• Wyatt Dawn MALS Detector and Orbit Recycle System (2022 model)

Comprehensive Bio-HPLC System with Advanced Detection Suite. This high-performance liquid chromatography (HPLC) system is meticulously configured for advanced biomolecular analysis, ensuring exceptional flexibility, sensitivity, and precision.

Key Components:

• Agilent 1290 Infinity II Bio Flexible Pump (G7131A): Designed with biocompatible materials, this pump delivers precise gradient formation from up to four solvents at pressures up to 1300 bar and flow rates up to 5 mL/min, making it ideal for applications involving high-salt and extreme pH conditions.
• Agilent 1290 Infinity II Bio Multisampler (G7137A): This versatile autosampler accommodates both vials and microplates, offering a capacity of up to 6144 samples. Its biocompatible sample flow path ensures the integrity of biomolecules and minimizes unwanted surface interactions.
• Agilent 1290 Infinity II Multicolumn Thermostat (G7116B): Provides precise temperature control for up to four columns, enhancing separation consistency and method versatility.
• Agilent 1290 Infinity II Diode Array Detector (G7117B): Enables comprehensive UV/Vis spectral acquisition with high sensitivity and a wide linear range, facilitating accurate detection and quantification of diverse analytes.
• Agilent 1260 Infinity II Fluorescence Detector Spectra (G7121B): Offers high-sensitivity detection of fluorescent compounds, with advanced spectral acquisition capabilities for detailed analysis.
• Wyatt Optilab Differential RID Refractive Index Detector (2022 model): A unique dRI detector for HPLC/GPC, providing 256 times the detection power and 50 times the dynamic range of traditional RI detectors. It measures the absolute refractive index of solvents, essential for accurate molar mass determination.
• Wyatt DAWN Multi-Angle Light Scattering (MALS) Detector with Orbit Recycle System (2022 model): This advanced detector determines the absolute molar mass and size of macromolecules and nanoparticles in solution, offering unparalleled accuracy for biotherapeutic characterization and polymer analysis.

This comprehensive Bio-HPLC system is ideally suited for:​

• Biotherapeutic Characterization: Accurately analyze proteins, peptides, and other biomolecules to ensure efficacy and safety.​
• Polymer Analysis: Determine molecular weights and distributions essential for material science applications.​
• Advanced Protein Studies: Investigate protein aggregation, conformation, and interactions critical for pharmaceutical development.​
• By integrating these state-of-the-art components, the system delivers robust performance and reliable results for the most demanding analytical tasks