Thermo TSQ Quantum Access MAX Triple Quadrupole Mass Spectrometer with Accela HPLC

The Thermo Scientific TSQ Quantum Access MAX triple stage quadrupole mass spectrometer is designed to meet the quantitative and qualitative challenges of a broad range of applications, including: pharmaceutical, environmental, food safety, clinical research, and forensics. Based on the widely used TSQ Quantum system, it sets the benchmark for sensitivity in its class, and provides unmatched analytical specificity.

Capabilities such as Highly Selective Reaction Monitoring (H-SRM) and highField Asymmetric waveform Ion Mobility Spectrometry (FAIMS) are available on the TSQ Quantum Access MAX™. Innovative technology such as Quantitation-Enhanced Data-Dependent MS/MS (QED-MS/MS) makes structural confirmation and quantitation easy, facilitating metabolite ID or multiresidue screens. Also standard is the new Reversed Energy Ramp (RER) scan, which ensures library-searchable, fragment-rich MS/MS spectra are produced routinely.

Standard Features

Thermo Scientific Ion Max API Source

• Enhanced sensitivity and ruggedness

• Sweep gas reduces chemical noise

• Optimal 60-degree spray angle for best sensitivity and ruggedness

• Interchangeable HESI-II and APCI ionization probes

• APPI/APCI combination probe

• Removable ion transfer tube provides vent-free maintenance

• High temperature, self-cleaning APCI heater employing state-of-the-art ceramic heater technology

• Automatic source recognition for ease of use and simplified data logging

Transfer Ion Optics

• Proprietary tube lens and noise reduction geometry

• Dual square quadrupole high efficiency transfer optics

Triple Quadrupole Mass Analyzer

• Mass range of 10–3000 daltons (Da)

• Patented Thermo Scientific HyperQuad mass analyzers provide superior and unique combination of resolution and sensitivity

• 90° high-efficiency square quadrupole collision cell for super fast SRMs

• CID gas pressure programmable through the software

• Variable peak width selection in all scan modes

• Scan rate of 5,000 µ/s

• Minimum SRM scan time of 1 ms

Scan Functions

• Full-scan MS in Q1 or Q3

• Selected Ion Monitoring (SIM) in Q1 or Q3

• Selected Reaction Monitoring (SRM)

• Retention time correction in real time for improved RSDs

• Product Ion Scanning

• Precursor Ion Scanning

• Neutral Loss Scanning

Advanced Scan Functions

• QED-MS/MS scanning

• Reversed Energy Ramp (RER) scanning

• Highly Selective Reaction Monitoring (H-SRM)

Acquisition

• Real-time high-speed digital signal processing eliminates high frequency noise

• Digital sampling rate up to 195,000 samples per second

• High-resolution centroiding

Detection System

• Proprietary detection system uses a fast switching (≤ 25 ms) post-acceleration conversion dynode with ±10 kV applied voltage

• Off-axis continuous dynode electron multiplier with increased dynamic range

• System integrated electron multiplier eliminates field emission and microphonic noise