Agilent 6410B MS/MS with Agilent 1200 front end HPLC

System Includes:

• G1379B Micro Degasser with solvent tray
• G1312A Binary pump
• G1367C HiP Autosampler SL+
• G1330B Autosampler Thermostat
• G1316B Thermostatted Column Compartment TCC
• (Optional) G1315B Diode Array Detector DAD
• Agilent G6410B Mass Spectrometer (US8471113XXX)
• Suitable software and PC

The Agilent 6410B LC/MS is a triple quadruple instrument where analytes are introduced into the ion source from a liquid eluent and are further converted into gaseous state molecules by the process of desorption. These molecules are then transferred through a vacuum into an ion transfer capillary and passed through the first quadrupole for mass filtering. From the first quadrupole, a precursor ion may be selected; this ion is further allowed to pass into a collision cell where collision induced dissociation (CID) occurs and the precursor ion is fragmented into various product ions. The third quadrupole acts as the secondary mass filter for selection of target ions after CID. The overall monitoring of a selected transition from precursor to product ion is known as single reaction monitoring, when multiple ions are monitored the term multiple reaction monitoring is used.