Thermo Scientific Q Exactive PLUS Orbitrap LC-MS/MS System (2017)

System includes:

• Thermo Scientific Q Exactive PLUS Orbitrap Mass Spectrometer
• Dionex UltiMate 3000 RS Front-End LC:
  • SRD-3400 Solvent Rack with 4 degasser channels (PN: 5035.9245)
  • NCS-3500RS Nano LC Pump with ProFlow Flow Meter and Column Compartment (PN: 5041.0010A)
  • WPS-3000TPL RS Rapid Separation Pulled-Loop Nano/Cap Thermostatted Well Plate Autosampler (PN: 5826.0020)
• Peak Scientific Genius NM32LA nitrogen generator 230v (PN: 10-6020)
• Sogevac SV40-65 BI FC Single-stage, oil-sealed rotary vane pump
• Thermo Scientific cover for rotary vane pump
• Amtek Powervar Power Conditioner ABC5000-2S (PN: 95208-92R)
• Amtek Powervar Power Distribution Unit PDU5800-2S (PN: 99021-35R)
• PC with software data

Thermo Scientific Q Exactive Plus Hybrid Quadrupole-Orbitrap Mass Spectrometer

Take Quanfirmation to the next level. The Thermo Scientific Q Exactive Hybrid Quadrupole-Orbitrap Mass Spectrometer introduced the revolutionary concept of Quanfirmation. The Q Exactive Plus Hybrid Quadrupole-Orbitrap Mass Spectrometer takes Quanfirmation to the next level with increased performance and new options that enhance applications from confident DMPK qual/quan screening studies to characterization of intact monoclonal antibodies.

Superior Quantitation

• Advanced quadrupole technology (AQT) improves precursor selection and transmission for more-accurate quantitation of low-abundance analytes in complex matrices
• Sophisticated data-independent acquisition (DIA) and parallel reaction monitoring (PRM) deliver reproducible quantitation with complete qualitative confidence
• An advanced active beam guide (AABG) reduces noise and extends maintenance intervals

Enhanced Analysis of Intact Proteins

• Optional intact protein mode provides superior trapping of large molecules for improved analysis of intact proteins and protein complexes
• Optional enhanced resolution ensures maximum ID confidence in top-down proteomics and lipidomics

High-Confidence Results

• HR/AM and full-scan capabilities capture all sample data, all of the time, enabling retrospective data analysis without need to re-run samples
• Resolving power up to 140,000 FWHM eliminates isobaric interferences, increasing confidence in results when analyzing samples in complex matrices
• Better than 1-ppm mass accuracy in full- and all-ion fragmentation (AIF) scan modes ensures confident compound identification
• Fast scanning at 12 Hz and spectral multiplexing suited to UHPLC applications
• Rapid polarity switching maximizes information obtained
• AIF and multiple dissociation techniques — in-source CID and HCD — aid in compound identification
• Mass range to 6000 m/z enhances detection of singly charged small molecules and biomolecules
• More than four orders of magnitude intrascan dynamic range, along with femtogram-level sensitivity, allow detection of trace-level and high-abundance compounds in the same scan

For Research Use Only. Not for use in diagnostic procedures.