Thermo TSQ Quantum Ultra Triple Quadrupole Mass Spectrometer

Quantify with outstanding accuracy using the Thermo Scientific TSQ Quantum Ultra triple quadrupole mass spectrometer. Achieve outstanding sensitivity and specificity without sacrificing versatility. The TSQ Quantum Ultra system is available with optional extended mass range (EMR), accurate mass (AM), and high-field asymmetric waveform ion mobility spectrometry (FAIMS) capabilities to meet the demands of the widest range of applications.

A 90-day warranty is included.

Specifications:

Sensitivity

Electrospray (HESI) at High Resolution 0.2 Da FWHM A 5 μL injection of a 200 fg/μL reserpine solution on a Hypersil GOLD aQ 20 X 2.1 mm 1.9 μm particle packed column at a flow rate of 300 μL/min 30:70:0.02 water/methanol/formic acid will produce a minimum signal-to-noise ratio of 3000:1 for the transition of the protonated molecule at m/z 609.3 to the fragment ion at m/z 195.1 when operated in selected reaction monitoring mode (SRM) with Q1 and Q3 resolution set to 0.2 and 0.7 Da FWHM respectively.

Atmospheric Pressure Chemical Ionization (APCI) and Atmospheric Pressure Photoionization (APPI) at High Resolution 0.2 Da FWHM A 5 μL injection of a 200 fg/μL reserpine solution on a Hypersil GOLD aQ 20 X 2.1 mm 1.9 μm particle packed column at a flow rate of 300 μL/min 30:70:0.02 water/methanol/formic acid will produce a minimum signal-to-noise ratio of 300:1 for the transition of the protonated molecule at m/z 609.3 to the fragment ion at m/z 195.1 when operated in selected reaction monitoring mode (SRM) with Q1 and Q3 resolution set to 0.2 and 0.7 Da FWHM respectively.

Mass Accuracy– TSQ Quantum Ultra AM

Infusion of a mixture of polyethylene glycols (PEGs) of average molecular weights 200, 400, 600, and 1000 at 50 pmoles/μL produces 27 ammoniated PEG ions from 124 to 1268 Da. Accurate mass data is generated on each of the 25 ions from 168 to 1224 Da using the neighboring peaks as internal lock masses. The mass of each ion is determined from the average of up to 100 scans and the error between the expected mass and the measured mass is expressed in mmu and ppm. The root mean square (RMS) average is computed from the errors of the 25 individual ions. The RMS error will be less than or equal to 5 ppm.

Mass Range

10–1500 Da (TSQ Quantum Ultra/Ultra AM)

10–3000 Da (TSQ Quantum Ultra EMR)

Resolution

7500 (FWHM) at m/z 508 of polytyrosine Resolution is continuously adjustable to better than 0.1 Da peak width (FWHM) across the entire mass range.

Mass Stability

The laboratory room temperature must be maintained between 15-27°C (59-81°F).

The optimum temperature of operation is between 18-21°C (65-70°F).

TSQ Quantum Ultra/Ultra EMR

Mass assignment will be within ±0.050 Da over a 24 hour period.

The room temperature may not change by more than 5°C (9°F) during this period.

TSQ Quantum Ultra AM

Mass assignment will be within ±0.025 Da over a 24 hour period.

The rate of change in temperature may not exceed 2°C per hour (3.6°F/hr) and not by more than 5°C (9 °F) during this period.